Isoflavon is a substance similar to estrogen, but differ in the OH bond. Substance is found in many plants, seeds, and vegetables. Isoflavon active substance consisting of isoflavon, lignan, and coumestan, but the most widely used in the field of health is isoflavon. Active substance is not only in the raw material, but also processed, such as tempe, know, etc.. In the body is active isoflavon similar to the hormone estrogen.
The in situ isoflavon proved that the action inhibisitirosin kinase that impedes growth and development so that cells can be used as prevention of cancer disease. Isoflavon mechanism in this case prevent the inhibition of topoisomerase 1, transcript 2 DNA replication prevent the DNA that produces proteins that are not normal. In addition, the property isoflavon various kardioprotektif for example, bone turnover, reproduction, etc.. Isoflavon can also use-right to prevent and reduce the risk of occurrence of breast cancer. While in the ovarium cancer isoflavon resistance to change because kemo-therapy by increasing the cell permeability to help so easy improved again and accelerate healing of treatment with chemotherapy. In the field of reproductive isoflavon terbukti improving menstrual pattern, painful menstruation, and the long period.
Fitoestrogen main target in the body of the first network is a system in the reproductive organs because of the amount of estrogen reseptor high enough. Menstruation effect on the phase fitoestrogen extend luteal phase. While in the premenopause phase fitoestrogen cause a beneficial effect estrogenik prevent breast cancer.
This is evidenced in epidemiologis that the incidence of breast cancer is lower in Asian nations that consume higher fitoestrogen from Western nations. In addition, the degree fitoestrogen in blood and urin Asian nations than Western nations. In addition, the phases of menopause fitoestrogen proven to reduce heat shock. Based on the research of 58 women who were given menopause soy flour and wheat flour for 12 sunday heat shock significantly reduced of 40% and 25%.
Research using tocopil containing 56 fitoestrogen 38 mg was given to 152 female menopause during the 26 - 29 months. The result decrease hot flush, night sweat, feel weak, and the increase in Libido.
Isoflavon not only a role in the reproductive organs but also play a role in heart health. During premenopause women have protection against disease kardiovaskular with the hormone estrogen protection against endotel. After entering the menopause when the hormone estrogen level decreases, the incidence of disease kardiovaskular women equal to men. Isoflavon mechanism kardiovaskular in preventing disease is through a decrease in cholesterol. Isoflavon terbukti lower total cholesterol, increase HDL, lower trigliserida, and prevent LDL cholesterol oxidation. As known in the LDL oxidation will become free radicals that can harm the wall plaque endotel so arise and there aterosklerosis. Isoflavon can be consumed in the form of the original form of soy, ginger nuts, sunflower seeds, etc.. While processed isoflavon can be consumed in the form of tempe, tahu, yoghurt, etc..
Menopause for women Calvonin capsule containing the active ingredients isoflavon extracts of pure herbs can be an alternative to replace the lost estrogen.
Isoflavon role for Women's Reproductive Health
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